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New study suggests better ROI for pretreatment CYP2D6 screening
Pharmacogenomics J. 2009 May 19. Intermediate metabolizer: increased side effects in psychoactive drug therapy. The key to cost-effectiveness of pretreatment CYP2D6 screening? Laika B, Leucht S, Heres...
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Michael Jackson’s Death Illustrates the Danger of Adverse Drug Reactions
The tragic death of Michael Jackson has the potential to create an important “learning moment” for physicians and patients. According to the Journal of American Medical Association, adverse drug...
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OurBlook Interview: Creating Tailor-Made Prescriptions for All Patients
Ashcraft: Creating Tailor-Made Prescriptions for All Patients Kristine Ashcraft, director of sales and marketing for Genelex Corp. in Seattle, explains how pharmacogenetics can ease the issues that...
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It’s Time for Tamoxifen CYP2D6 Testing to Become the Standard of Care
JAMA released more research today that further confirms the importance of CYP2D6 testing to determine tamoxifen efficacy. Full details at http://jama.ama-assn.org/cgi/content/short/302/13/1429. The...
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The NFCR co-authored this press release to help raise awareness if tamoxifen...
(SEATTLE) – Five hundred thousand women in the U.S. are taking tamoxifen to prevent breast cancer recurrence. Almost half of them have a gene variation that reduces the effectiveness of the drug. For...
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Tipping Point for Personalized Medicine?
It’s been a busy week for personalized medicine! First, the FDA announced a black box for Plavix warning physicians of treament failures in CYP2C19 poor metabolizers representing up to 14% of their...
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Effects of CYP2C19 Genotype on Outcomes of Clopidogrel Treatment
I have to question the conclusions drawn in this study. The number of patients found to have variant alleles does not compute. Of the 5059 patients genotyped, only 25.5% had a variant allele...
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For Some Troops, Powerful Drug Cocktails Have Deadly Results
http://www.nytimes.com/2011/02/13/us/13drugs.html?_r=1&hpw The tragic deaths described in these stories seem largely avoidable, given what we know about drug interactions, pharmacogenetics and the...
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Leading Cardiologists Say It’s Time to Rethink Genetic Testing for CYP2C19...
“The thing that hit me in the face, was that virtually all the events were in those homozygotes” - Dr. C. Michael Gibson, Duke University Dr....
View ArticleAdvantages of Laparoscopic Surgery
In days past, surgeons had to make large cuts to adequately see and work inside patients’ bodies. .In the 1980s, new technologies like tiny cameras and micro-instruments allowed surgeons to minimize...
View ArticleAmerican Cancer Society – how you can Join the Fight against Cancer
Cancer is an incredibly vicious disease that has impacted most everyone in the country in some way. Whether you yourself has been a victim or one of your friends or family members, there isn’t a single...
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The American Heart Association was founded in 1942 by a group of six cardiologists. The organization promotes awareness and funds research in order to fight against disability and death caused by...
View ArticleAmerican Red Cross Volunteer Opportunities
There is no greater cause than the American Red Cross. Through their various programs they have been able to save countless lives, not just in the United States, but around the world. The efforts that...
View ArticleAortic Dissection – Life Dissected
I used to think about this event every minute of the day, now we are probably up to every hour or so. I am glad that it doesn’t occupy every minute any more, but I do want to document it in writing. It...
View ArticleAre Durable Powers of Attorney for Health Care Good for Patients?
It is important to know that there are two types of Power of Attorney .One is a limited Power of Attorney and the other is an enduring (durable) Power of Attorney . Basically a limited Power of...
View ArticleAre Electronic Cigarettes Safe ?
Electronic cigarettes give new hope to millions of smokers who want to quit or are looking for a healthier alternative. To form an educated opinion and determine whether or not electronic cigarettes...
View ArticleArythmia and Stress Experiences
Arrhythmia can be caused, or triggered by a number of things, stress being one of them. They can be a sign of a serious condition or they can happen in otherwise healthy hearts. They can slow your...
View ArticleYour Child and Scoliosis
None of my sons have scoliosis. I had it as a child, worse than any of my relatives with it, and still have it today. Mine is the progressive kind, and causes pain and height loss even now, some fifty...
View ArticleTry Out Different Baby Formula Samples
Having a baby is a very exciting time in your life. When you are being gifted a little bundle of joy, it is important that you plan ahead so that you are ready when your newborn arrives. There are many...
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